Table 1.
Serum cytokine antibody array representing the significantly downregulated proteins in the Synbio-glucan topical treatment group compared to the positive control group based on the fold-change rank.
| Rank | Antibody Name | Fold-Change | Gene Symbol | Swiss-Prot Entry |
|---|---|---|---|---|
| Downregulated | ||||
| 1 | IFN-beta | 0.354 | Ifnb1 | P01575 |
| 2 | GDF-8 | 0.377 | Mstn | O08689 |
| 3 | Common gamma Chain/IL-2 R gamma | 0.408 | Il2rg | P34902 |
| 4 | Endostatin | 0.412 | Col18a1 | P39061 |
| 5 | IGFBP-3 | 0.423 | Igfbp3 | P47878 |
| 6 | SPARC | 0.424 | Sparc | P07214 |
| 7 | WISP-1/CCN4 | 0.432 | Wisp1 | O54775 |
| 8 | TLR2 | 0.440 | Tlr2 | Q9QUN7 |
| 9 | SLPI | 0.450 | Slpi | P97430 |
| 10 | MIP2 | 0.453 | Cxcl2 | P10889 |
| 11 | VEGF-B | 0.456 | Vegfb | P49766 |
| 12 | CCL28 | 0.458 | Ccl28 | Q9JIL2 |
| 13 | ICAM-1 | 0.460 | Icam1 | P13597 |
| 14 | Fas/TNFRSF6 | 0.461 | Fas | P25446 |
| 15 | CXCR6 | 0.465 | Cxcr6 | Q9EQ16 |
| 16 | IL-1 RI | 0.475 | Il1r1 | P13504 |
| 17 | IGFBP-1 | 0.475 | Igfbp1 | P47876 |
| 18 | b FGF | 0.482 | Fgf2 | P15655 |
| 19 | Prolactin | 0.483 | Prl | P06879 |
| 20 | M-CSF | 0.485 | Csf1 | P07141 |
| 21 | TGF-beta RII | 0.485 | Tgfbr2 | Q62312 |
| 22 | CRP | 0.488 | Crp | P14847 |
| 23 | Lymphotoxin beta R/TNFRSF3 | 0.488 | Ltbr | P50284 |
| 24 | Frizzled-6 | 0.496 | Fzd6 | Q61089 |
| 25 | IL-27 | 0.499 | Il27 | Q8K3I6 |
| 26 | IL-23 R | 0.499 | Il23r | Q8K4B4 |
| 27 | TCCR/WSX-1 | 0.499 | Il27ra | O70394 |