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. 2021 Apr 2;9(4):373. doi: 10.3390/biomedicines9040373
Elaborated Phrasese Abbreviations
Pancreatic ductal adenocarcinoma PDAC
programmed cell death protein-1 PD-1
programmed cell death ligand-1 PD-L1
cytotoxic T-lymphocyte-associated protein 4 CTLA-4
Guanine nucleotide exchange factors GEFs
GTPase activating proteins GAPs
mitogen-activated protein kinase MAPK
extracellular signal-regulated kinase Erk
phosphoinositide 3-kinases PI3Ks
Phosphoinositide-dependent kinase-1 PDK-1
Ral guanine nucleotide exchange factors RalGEFs
epidermal growth factor EGF
epidermal growth factor receptor EGFR
fibroblast growth factor FGF
FGF receptor FGFR
insulin-like growth factor IGF
insulin-like growth factor receptor IGFR
platelet-derived growth factor PDGF
vascular endothelial growth factor VEGF
transforming growth factor-α TGF-α
Hypoxia-inducible factor 1-alpha HIF1-α
Snail family of zinc finger transcription factors Snail 1 and 2
zinc-finger-enhancer binding protein Zeb-1 and 2
Casein kinase 1 CK1
lymphoid enhancer factor LEF
tumor microenvironment TME
antigen-presenting cells APCs
interferon-γ IFN-γ
Interleukin-2 IL-2
tumor-infiltrating lymphocytes TILs
Lymphocyte Activation Gene 3 LAG3
basic helix-loop-helix bHLH
Regulatory T cells Tregs
plasmacytoid dendritic cells pDCs
V-domain Ig suppressor of T cell activation VISTA
Signal transducer and activator of transcription 3 STAT3
major histocompatibility complex MHC
Nonsmall-cell lung carcinoma NSCLC
Renal cell carcinoma RCC
Hepatocellular carcinoma HCC
High microsatellite instability MSI-H
Microsatellite instable MSI
carboxy terminal Cys2His2 C2H2