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. 2021 Mar 25;13(4):554. doi: 10.3390/v13040554

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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An electron microscopy analysis of the ultrathin abortion material sections showed damaged organelles and virus-like particles: (A) Electron micrographs of CHIKV-infected cells showing dispersed chromatin in the nuclei (N), mitochondria (M) with fewer cristae and (B) endoplasmic reticulum (ER) exhibiting dilated cisterns. (C) A decidual cell presenting a rarefied cytoplasm with an absence of organelles and starting to produce apoptotic bodies (Ap). (D) A decidual cell in apoptosis. (E,F) A cell with vesicles surrounding a cluster of virions in the cytoplasm (white arrows). (G) In the same field, at a higher magnitude, these CHIKV virus-like particles (red arrows) are located near a ruptured ER. The scale bar indicates that the particles are approximately 40–50 nm in size, consistent with the CHIKV.