Table 2.
Composition and physicochemical characteristics of liposome samples as assessed by dynamic light scattering using the Malvern equipment.
| Sample Composition, by mol |
Z-Average Size, nm 1 | PdI Width, nm (Average) |
PdI | Zeta-Potential, mV 2 |
|---|---|---|---|---|
| ePC | 121.3 ± 2.4 | 35.2 ± 1.1 | 0.084 ± 0.003 | −1.4 ± 1.6 |
| ePC–MlphDG, 9:1 | 117.3 ± 2.2 | 33.1 ± 1.1 | 0.079 ± 0.003 | +18.4 ± 1.9 |
| ePC–PI, 9:1 | 104.4 ± 1.8 | 28.5 ± 2.6 | 0.068 ± 0.016 | −48.8 ± 2.6 |
| ePC–MlphDG–PI, 8:1:1 | 121.3 ± 2.3 | 34.8 ± 1.1 | 0.082 ± 0.003 | −25.3 ± 1.9 |
1 Mean values ± SD are presented. Size distribution curves can be found in Supplementary Materials, Figure S1. 2 Data for 200-nm liposomes were obtained using ZetaPALS analyzer (Brookhaven Instruments Corp.).