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. 2021 Mar 30;10(4):279. doi: 10.3390/biology10040279

Figure 2.

Figure 2

Regulation of gene expression by NFX1. Model of NFX1 (NFX1-91 and NFX1-123) mediated gene regulation. NFX1-91 binds to DNA to regulate gene expression either through transcriptional repression or activation. NFX1-123 binds to RNA to regulate gene expression through post-transcriptional regulation. NFX1-123 also interacts with other RNA binding and processing proteins, including cap-binding proteins (shown in yellow and teal) and cytoplasmic poly(A) binding proteins (shown in red). The cellular pathways affected by NFX1 are shown.