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Ongoing trials that are investigating the role of focal adhesion kinase (FAK) inhibitors in PDAC treatment.
| FAK Inhibitor | Additional Therapy | Phase | NCT No. | Participants No. | Recruiting |
|---|---|---|---|---|---|
| Defactinib | Pembrolizumab+ | I | NCT02546531 | 43 | No |
| Gemcitabine | |||||
| Defactinib | Pembrolizumab | I/II | NCT02758587 | 59 | Yes |
| GSK2256098 | Trametinib | II | NCT02428270 | 16 | No |
FAK: focal adhesion kinase.
