Table 3.
Trial | Population | No. Patients | Drug | Follow-Up (Years) | Ldl Reduction % | Cv Event Reduction % | p Value |
---|---|---|---|---|---|---|---|
SHARP | CKD patients | 9270 | Simvastatin 20 mg/ ezetimibe | 4.9 | 55% | 17% | 0.0021 |
4D | Hemodialysis | 1255 | Atorvastatin 20 mg | 4 | 42% | - | 0.35 |
AURORA | Hemodialysis | 2776 | Rosuvastatin 10 mg | 3.8 | 43% | - | 0.59 |
LDL: Low-density lipoprotein; CKD: Chronic Kidney Disease; CV: Cardiovascular; SHARP: Study of Heart and Renal Protection; 4D: Die Deutsche Diabetes Dialyse Studie; AURORA: An Assessment of Survival and Cardiovascular Events.