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. 2021 Apr 6;10(4):816. doi: 10.3390/cells10040816

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of chemotherapeutic drugs on the growth of MIA-PaCa-2 + WT-GSK-3β, MIA-PaCa-2 + KD-GSK-3β and MIA-PaCa-2 + pLXSN cells. The effects of doxorubicin (Panel (A)), daunorubicin (Panel (B)), mitoxantrone (Panel (C)), and etoposide (Panel (D)) on MIA-PaCa-2 + WT-GSK-3β (solid red boxes), MIA-PaCa-2 + KD-GSK-3β (solid blue triangles) and MIA-PaCa-2 + pLXSN Cells (solid green circles) were examined by MTT analysis. The MIA-PaCa-2 + WT-GSK-3β, MIA-PaCa-2 + KD-GSK-3β, and MIA-PaCa-2 + pLXSN cells in each panel were all examined at the same time period. These experiments were repeated 4 times and similar results were obtained. Statistical analyses were performed via the Student’s T test on the means and standard deviations of various treatment groups. *** p < 0.0001, ** p < 0.005, and * p < 0.05.