Table 6.
Risk factors of patients with first-ever acute ischemic stroke at different altitudes.
| Penglai (n = 697) | Huzhu (n = 122) | Yushu (n = 73) | p Value | |
|---|---|---|---|---|
| Hypertension [n (%)] | 450 (64.6) | 89 (73.0) | 51 (69.9) | 0.153 |
| Systolic pressure (mmHg) | 156.04 ± 23.35 | 142.75 ± 21.78 | 148.49 ± 25.99 | <0.001 0.016 |
| Diastolic pressure (mmHg) | 89.98 ± 12.99 | 93.07 ± 17.79 | 95.44 ± 17.86 | |
| Mean arterial pressure (mmHg) | 112.00 ± 15.06 | 109.63 ± 18.06 | 113.12 ± 19.73 | 0.393 |
| Pulse pressure (mmHg) | 66.06 ± 17.44 | 49.69 ± 13.91 | 53.05 ± 14.75 | <0.001 |
| Diabetes mellitus [n (%)] | 201 (28.8) | 21 (17.2) | 7 (9.6) | <0.001 |
| Glucose level (mmol/L) | 6.85 ± 3.01 | 6.09 ± 3.68 | 6.52 ± 2.59 | <0.001 |
| Coronary heart disease [n (%)] | 100 (14.3) | 2 (1.6) | 3 (4.1) | <0.001 |
| Hyperlipidemia [n (%)] | 144 (20.2) | 21 (17.2) | 6 (8.2) | 0.031 |
| Hypertriglyceridemia [n (%)] | 81 (11.6) | 16 (13.1) | 4 (5.5) | 0.191 |
| Hypercholesterolemia [n (%)] | 95 (13.6) | 8 (6.6) | 2 (2.7) | 0.018 |
| LDL-C (mmol/L) | 2.57 ± 0.77 | 2.45 ± 0.85 | 2.74 ± 0.91 | 0.028 |
| HDL-C (mmol/L) | 1.27 ± 0.32 | 1.44 ± 0.38 | 1.10 ± 0.35 | <0.001 |
| TG (mmol/L) | 1.50 ± 1.40 | 1.44 ± 1.19 | 1.39 ± 0.80 | 0.242 |
| CHOL (mmol/L) | 4.94 ± 1.22 | 4.35 ± 1.13 | 4.27 ± 1.02 | <0.001 |
| Hyperhomocysteinemia [n (%)] | 95 (13.6) | 51 (41.8) | - | <0.001 |
| Homocysteine level (μmol/L) | 13.31 ± 8.76 | 15.82 ± 7.74 | - | <0.001 |
| Smoking [n (%)] | 232 (33.1) | 61 (50.0) | - | 0.023 |
| Alcohol consumption [n (%)] | 196 (28.1) | 12 (27.3) | - | 0.093 |
| Atrial fibrillation [n (%)] | 57 (8.2) | 11 (9.0) | 3 (4.1) | 0.462 |
| Polycythemia [n (%)] | 0 | 17 (13.9) | 7 (9.6) | <0.001 |
| Hemoglobin level (g/L) | 138.22 ± 18.04 | 172.87 ± 31.57 | 171.81 ± 29.55 | <0.001 |
| Red blood cell count (*1012/L) | 4.60 ± 0.59 | 5.40 ± 0.84 | 6.24 ± 1.00 | <0.001 |
| Hematocrit | 41.59 ± 5.19 | 50.24 ± 9.42 | 49.02 ± 8.06 | <0.001 |
| CRP (mg/L) | 7.92 ± 24.53 | 16.62 ± 16.40 | 18.67 ± 20.38 | <0.001 |
LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; TG: triglycerides; CHOL: Total cholesterol; CRP: C reactive protein.