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. 2021 Apr 6;10(4):823. doi: 10.3390/cells10040823

Figure 6.

Figure 6

C. minuta DSM33407 maintains gut barrier integrity in both in vivo and in vitro preclinical models. Fold change expression of colonic tight junction proteins Occludin (Ocln) (A), Claudin 1 (Cldn1) (B), Claudin 2 (Cldn2) (C), and Zonula occludens-1 (Zo1) (D) in a DIO mouse model after 40 days of treatment (n = 6). (E) In vitro Trans-Epithelial Electrical Resistance (TEER) upon exposure to the proinflammatory cytokine TNF-a. Statistics: one-way ANOVA followed by Tukey’s (A–D) or Dunett’s (E) multiple comparisons; for all: * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.