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. 2021 Apr 6;10(4):438. doi: 10.3390/pathogens10040438

Figure 3.

Figure 3

Mapping of peptide microarray reactive antibodies on the S, M, and N-proteins. (a) IgG and IgA epitopes derived from all four patients on the S (domains from [15]), M, and N proteins (see Supplementary Materials A Table S3). (b–d) A 3D view of the S GP structure (in blue) with the herein identified IgA (highlighted in orange), IgG (highlighted in magenta), and overlapping (highlighted in yellow) epitopes derived from all nine SARS-CoV-2 patient samples (generated with PyMOL from Protein Data Bank file 6vxx—cryo-EM structure of S GP [16]). (b) Top view, (c) side view, and (d) alternate side view of S GP trimer.