Table 5.
The adjusted odds ratios of fetal growth restriction (FGR) for pre-pregnancy BMI, in the whole cohort and subgroups.
| Odds Ratios of FGR for BMI Categories | |||
|---|---|---|---|
| Birth Weight | Cases/ Controls |
OR (95% CI:); p | AOR * (95% CI:); p |
| FGR (n = 21) ** | |||
| Whole cohort | |||
| Obesity | 5/91 | 2.64 (0.91−7.7); 0.075 | 3.12 (1.02−9.54); 0.045 |
| Overweight | 0/170 | NC | NC |
| Normal BMI | 12/576 | 1 | 1 |
| Underweight | 4/43 | 4.47 (1.38−14.4); 0.012 | 3.84 (1.13−13.0); 0.031 |
| ‘Healthy’ subgroup | |||
| Obesity | 1/36 | 1.57 (0.19−12.9); 0.675 | 2.37 (0.27−20.84); 0.438 |
| Overweight | 0/118 | NC | NC |
| Normal BMI | 8/452 | 1 | 1 |
| Underweight | 2/33 | 3.42 (0.7−16.78); 0.129 | 2.52 (0.49−12.97); 0.268 |
| GWG in the range | |||
| Obesity | 1/24 | 3.33 (0.33−33.3); 0.305 | 4.06 (0.38−43.07); 0.245 |
| Overweight | 0/47 | NC | NC |
| Normal BMI | 3/240 | 1 | 1 |
| Underweight | 3/17 | 14.12 (2.65−75.3); 0.002 | 11.82 (1.95−71.6); 0.007 |
* AOR: adjusted odds ratios (with 95% CI: confidence intervals) calculated in the multiple logistic regression (p-value < 0.05 was assumed to be significant) and the results were obtained after adjustment for: maternal age, primiparity, GWG above the range, and prior pregnancy induced hypertension (GWG were excluded in the subgroup of the GWG in the range); ** the analysis covered mothers with FGR newborns vs. mothers with newborns without FGR. FGR: Fetal growth restriction. ‘Healthy’ subgroup: Women who did not develop either diabetes or hypertension in the current pregnancy; BMI: Body mass index; GWG: Gestational weight gain.