Table 6.

Concentrations of extracts (µg/mL) that induce inhibition of biological activity in 50% cells (IC₅₀), 50% growth inhibition (GI₅₀), total growth inhibition (TGI) and 50% lethality (LC₅₀) in the HeLa cell line, expressed as X ± SD. SI: selectivity index.

HeLa		1E	2E	3E	4E	5E	6E
IC50	24 h	>100	>100	>100	>100	>100	>100
	48 h	22.72 ± 3.53	16.97 ± 2.10	44.38 ± 1.96	16.74 ± 1.43	25.90 ± 4.60	25.32 ± 7.80
	72 h	19.53 ± 1.03	15.15 ± 1.72	33.43 ± 1.36	14.97 ± 0.78	18.73 ± 0.53	20.04 ± 5.10
SI	24 h	0.97	1.52	1.71	1.31	1.10	3.61
	48 h	14.19	20.14	12.08	19.61	8.34	11.87
	72 h	12.17	13.87	8.30	15.04	11.31	7.82
GI50	24 h	6.95 ±0.95	6.00 ± 0.34	98.09 ± 11.08	5.56 ± 0.18	7.67 ± 1.45	7.46 ± 0.99
	48 h	4.91 ± 0.84	3.49 ± 0.46	65.64 ± 3.66	2.54 ± 0.45	5.61 ± 1.22	5.75 ± 0.68
	72 h	0.86 ± 0.51	<0.3	59.38 ± 1.85	<0.3	4.97 ± 0.54	4.76 ± 0.52
TGI	24 h	16.90 ± 4.96	14.67 ± 0.58	>100	12.91 ± 0.44	47.25 ± 5.66	27.55 ± 1.89
	48 h	13.60 ± 1.75	11.00 ± 0.56	>100	9.18 ± 0.59	19.90 ± 4.38	16.77 ± 1.52
	72 h	13.27 ± 1.33	1.69 ± 0.36	>100	<0.3	18.42 ± 3.57	13.63 ± 1.26
LC50	24 h	>100	>100	>100	>100	>100	>100
	48 h	61.09 ± 16.15	35.65 ± 1.16	>100	27.07 ± 1.56	63.66 ± 2.30	41.15 ± 6.75
	72 h	43.19 ± 10.03	26.02 ± 2.88	>100	20.28 ± 1.10	60.65 ± 1.59	31.20 ± 5.93