Table 1.
Cytogenetics in CD34+ cells grown for 3 days in un-/fractionated medium conditioned by 2 Gy irradiated mesenchymal stromal cells. CM, conditioned medium; NA, not assessed; Pt, patient; [number] = number of metaphases.
| Pt | Age/ | Cytogenetics CD34+ Cells | Cytogenetics CD34+ Cells | Cytogenetics CD34+ Cells | Cytogenetics CD34+ Cells | ||||
|---|---|---|---|---|---|---|---|---|---|
| Sex | No Fractionation | <10 kDa | 10–100 kDa | >100 kDa | |||||
| Control | CM | Control | CM | Control | CM | Control | CM | ||
| #1 | 84/♀ | 46,XX[25] | 46,XX[20] 53,XX,+1,+2,+5,+6,+14,+21,+22[1] 92,XXXX[4] |
46,XX[20] | 46,XX[25] | 46,XX[25] | 46,XX[22] 92,XXXX[3] |
NA | NA |
| #2 | 65/♂ | 46,XY[25] | 46,XY[20] 92,XXXX[1] 184,XXXXYYYY,chtb(11)(q23)[1] 46,XY,dup(13q)[1] 47,XY,+21,chtb(11)(p12)[1] 46,XY,chtb(9)(12)[1] |
46,XY[25] | 46,XY[22] | 46,XY[25] | 46,XY[21] 92,XXXX[2] 69,XXY[1] 47,XY,+3[1] |
46,XY[25] | 46,XY[25] |
| #3 | 62/♂ | 46,XY[25] | 46,XY[22] 92,XXYY[3] |
46,XY[25] | 46,XY[25] | 46,XY[25] | 46,XY[20] 92,XXYY[3] 46,XY,chtb(5)(q33)[1] 46,XY,+f[1] |
46,XY[25] | 46,XY[25] |
| #4 | 62/♂ | 46,XY[25] | 46,XY[21] 92,XXYY[3] 92,XXYY,chtb(2p)[1] |
46,XY[25] | 46,XY[23] 46,XY,chtb(14q)[1] |
46,XY[25] | 46,XY[22] 92,XXYY[1] 184,XXXXYYYY[1] 46,XY,chtb(7p)[1] |
46,XY[23] 184,XXXXYYYY[2] |
46,XY[25] |
| #5 | 85/♂ | 46,XY[13] 45,X,-Y[12] |
46,XY[10] 45,X,-Y[12] 90,XX,-Y,-Y[1] 92,XXYY[1] 184,XXXXYYYY[1] |
46,XY[5] 45,X,-Y[20] |
46,XY[7] 45,X,-Y[18] |
46,XY[21] 45,X,-Y[4] |
46,XY[18] 45,X,-Y[3] 92,XXYY[2] 47,XY,+2[1] 50,XY,+1,+7,+9,+14[1] |
46,XY[10] 45,X,-Y[15] |
46,XY[13] 45,X,-Y[7] 92,XXYY[1] 90,XX,-Y,-Y[1] |
| #6 | 52/♂ | 46,XY[25] | 46,XY[22] 92,XXYY[2] 184,XXXXYYYY[1] |
46,XY[25] | 46,XY[24] 46,XY,+f[1] |
46,XY[21] | 46,XY[21] 92,XXYY[3] 184,XXXXYYYY[1] |
46,XY[25] | 46,XY[25] |