Table 1.

Comparison of characteristics among patients diagnosed with HPV16 positive-oropharynx cancer (PROVE study) and healthy individuals with detectable oral HPV16 DNA (NHANES). IQR = Interquartile range.

Patient Characteristics	HPV16-OPC n = 131		Oral HPV16 in healthy individuals n = 159		P-value
	N	%	N	%
Age (in years):					< 0.001
18 – 29	1	0.8	25	15.7
30 – 39	3	2.3	30	18.9
40 – 49	25	19.1	34	21.4
50 – 59	60	45.8	38	23.9
60 – 69	42	32.1	32	20.1
Sex					0.99
Male	112	85.5	136	85.5
Female	19	14.5	23	14.5
Race and Ethnicity					< 0.001
White non-Hispanic	116	88.5	83	52.2
Black non-Hispanic	8	6.1	35	22.0
Hispanic any race	4	3.1	31	19.5
Other	3	2.3	10	6.3
Cigarette Use			(n = 157)		< 0.001
Never	62	47.3	59	37.6
Current	9	6.9	66	42.0
Former	60	45.8	32	20.4
Alcohol Use	(n = 111)		(n = 159)		< 0.001
Never	2	1.8	2	1.3
Current	57	51.4	121	76.1
Former	52	46.8	36	22.6
Ever Illegal Drug Use	(n = 130)		(n = 145)		< 0.001
No	25	19.2	95	65.5
Yes	105	80.8	50	34.5
Lifetime Sex Partners			(n = 144)		0.06
Median (IQR)	20 (8 – 45)		15 (6 – 35)
Lifetime Oral Sex Partners			(n = 112)		0.17
Median (IQR)	10 (4 – 25)		8.5 (3 – 25.5)
Lifetime Vaginal Sex Partners	(n = 125)		(n = 109)		0.1
Median (IQR)	20 (8 – 35)		15 (6 – 30)