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Cellular accumulation of prodrugs 2–5 and cisplatin (µg Pt/106 cells) on HCT-116 (colorectal carcinoma) and MDA-MB-231 (triple negative adenocarcinoma) cell lines.
| Cellular Uptake, µg Pt/106 Cells | ||
|---|---|---|
| Compound/Cell line | HCT-116 | MDA-MB-231 |
| Cisplatin | 0.008 ± 0.001 | 0.013 ± 0.009 |
| 2 | 0.26 ± 0.04 | 0.4 ± 0.1 |
| 3 | 0.096 ± 0.007 | 0.17 ± 0.03 |
| 4 | 0.014 ± 0.001 | 0.033 ± 0.009 |
| 5 | 0.18 ± 0.01 | 0.27 ± 0.03 |
