Table 6.
Multivariate Cox regression for death in association with OPSCC. Table 6 shows the influence of the following variables on death due to OPSCC and/or SPT after OPSCC: tumor HPV positivity (negative = 0, positive = 1), smoking status (0 = <10 py, 1 = ≥10 py), alcohol status (0 = no alcohol abuse, 1 = alcohol abuse), age (in years), SPT development (0= no SPT, 1 = SPT), therapy mode (1 = surgery, 2 = RT, 3 = surgery + RT, 4 = surgery + RT + chemotherapy, 5 = surgery + chemotherapy), and UICC stage of the index OPSCC (1 = stage I, 2 = stage II, 3 = stage III, 4 = stage IVa, 5 = stage IVb). Abbreviations: CI = confidence interval, HR = hazard ratio, py = pack years, RT = radiotherapy.
| Multivariate Cox Regression for Death Associated with OPSCC | Death Associated with OPSCC | |
|---|---|---|
| Parameter | HR (95% CI) |
p-Value |
| Tumor HPV-positivity | 0.519 0.733–1.459) |
0.195 |
| Smoking (>10 py) | 1.634 (0.372–7.182) |
0.515 |
| Alcohol abuse | 1.248 (0.462–3.373) |
0.662 |
| Age | 1.024 (0.981–1.069) |
0.276 |
| SPT development | 0.978 (0.404–2.364) |
0.960 |
| Treatment of index tumor | 1.034 (0.733–1.459) |
0.850 |
| Index UICC stage | 0.871 (0.580–1.308) |
0.505 |
| Number of observations | 88 | |