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. 2021 Apr 7;9(4):427. doi: 10.3390/healthcare9040427

Table 3.

GRADE assessments for the certainty of evidence.

Outcome Study Design RoB 1 Publication Bias Inconsistency Indirectness Imprecision Quality of Evidence Recommendation
ROM 11 RCTs, 452 participants in meta-analysis. Randomization—low in four articles, moderate in one, and high in six. No publication bias. 9 RCTs showed improvements in ROM in both groups.
2 RCTs showed no changes in ROM in either group.
11 RCTs
showed effects of equal magnitude for ST and stretching. 2
No serious indirectness. Moderate. 3 Moderate.
⨁⨁⨁
Moderate recommendation for either strength training or stretching 4.
No recommendation for choosing one of the protocols over the other, as their efficacy in ROM gains was statistically not different.
Deviations from intended interventions—Low.
Missing outcome data—Low.
Measurement of the outcome—low in six articles and high in five.
Selection of the reported results—Low.

1—Meta-analyses moderated by RoB showed no differences between studies with low and high risk. 2—Because ROM is a continuous variable, high heterogeneity was expected. However, this heterogeneity is mostly between small and large beneficial effects. No adverse effects were reported. 3—Expected because ROM is a continuous variable. Furthermore, imprecision referred to small to large beneficial effects. 4—Both strength training and stretching presented benefits without reported adverse effects.