Table 2.
Additional CT findings, clinical and laboratory findings, and treatment outcomes of the three morphological types of amebic liver abscesses
Variables | Type I (n = 74) |
Type II (n = 31) |
Type III (n = 7) |
p-value |
---|---|---|---|---|
Additional CT findings | ||||
Size of abscess (cm) | 10.1 ± 2.5 | 8.6 ± 1.4 | 9.7 ± 1.9 | 0.010 |
Number of abscesses | 2.4 ± 2.4 | 1.4 ± 0.9 | 1.1 ± 0.4 | 0.039 |
Intracavitary hemorrhage | 4 (5%) | 1(3%) | 0 | 0.744 |
Intrahepatic ductal dilations | 2 (3%) | 0 | 0 | 0.593 |
Intracavitary air | 3 (4%) | 0 | 0 | 0.453 |
Rupture | 42 (57%) | 2 (6%) | 0 | < 0.001 |
Ascites | 23 (31%) | 2 (6%) | 0 | 0.007 |
Colonic manifestations | 28 (38%) | 4 (13%) | 0 | 0.008 |
Pleural effusion | 42 (57%) | 4 (13%) | 0 | < 0.001 |
Clinical findings | ||||
Age (years) | 44.5 ± 13.4 | 41.1 ± 9.1 | 39.1 ± 5.6 | 0.277 |
Duration of symptoms (days) | 10.5 ± 4.4 | 27.6 ± 6.5 | 41.5 ± 5.2 | < 0.001 |
Abdominal pain | 74 (100%) | 31 (100%) | 7 (100%) | |
Fever | 62 (83%) | 12 (39%) | 0 | < 0.001 |
Laboratory findings | ||||
TLC (/μL) | 24,996 ± 9,743 | 12,620 ± 4,826 | 8,325 ± 2,637 | < 0.001 |
Total bilirubin (mg/dL) | 2.4 ± 1.2 | 1.17 ± 0.59 | 0.54 ± 0.22 | < 0.001 |
Serum albumin (g/dL) | 1.96 ± 0.48 | 2.74 ± 0.56 | 2.43 ± 0.37 | < 0.001 |
AST (U/L) | 153.1 ± 125.6 | 54.6 ± 28.4 | 37.1 ± 18.4 | < 0.001 |
ALT (U/L) | 123.7 ± 118.9 | 52.9 ± 21.1 | 31.4 ± 5.2 | 0.004 |
ALP(U/L) | 343.6 ± 146.01 | 296.3 ± 110.7 | 254.7 ± 59.5 | 0.554 |
Treatment and outcomes | ||||
Inpatient hospital admission | 67 (90.5%) | 11 (35.5%) | 1 (14.3%) | < 0.001 |
Intensive care unit admission | 15 (20.3%) | 0 | 0 | < 0.012 |
Length of hospital stay (days) | 10.7 ± 3.44 | 6.1 ± 1.9 | 3 | < 0.001 |
Drug alone | 14 (19%) | 15(48%) | 0 | 0.002 |
Drainage | 60 (81%) | 16 (52%) | 7 (100%) | 0.002 |
Surgery | 1 (1%) | 0 | 0 | 0.772 |
Mortality | 2 (3%) | 0 | 0 | 0.593 |
P values in bold indicate statistically significant difference
Data are presented as n (%) or mean ± standard deviation
TLC total leukocyte counts, ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase