2D	Two-dimensional
3D	Three-dimensional
AJCC	American Joint Commission on Cancer
AKT	Protein kinase B
BCL-2	B-cell lymphoma-2
BCL-XL	B-cell lymphoma-extra large protein
BRAF	v-Raf murine sarcoma viral oncogene homolog B
CDKN2A	Cyclin-dependent kinase inhibitor 2A
CTCs	Circulating tumor cells
ctDNA	Circulating tumor DNA
CTLA-4	T-lymphocyte-associated protein
CT	Computed tomography
DDR	DNA damage repair
EMT	Epithelial mesenchymal transition
EpCAM	Epithelial cell adhesion molecule
ERK	Extracellular Signal-Regulated Kinase
FDA	Food and Drug Administration
HIF-1α	Hypoxia-inducible factor-1α
HiRIEF LC-MS/MS	High-resolution isoelectric focusing liquid chromatography-mass spectrometry
HR	Homologous recombination
ICI	Immune checkpoint inhibitor
IFN	Interferon
IL	Interleukin
IMPRES	IMmuno-PREdictive Score
ITS	Immunotherapy score
KIT	v-kit Hardy–Zuckerman 4 feline sarcoma viral oncogene homolog
LDH	lactate dehydrogenase
MAP3K	Mitogen-activated protein kinase kinase
MAPK	Mitogen-activated protein kinase
MCL-1	Myeloid leukemia cell differentiation
MEK	Mitogen-activated protein kinase kinase
MHC	Major histocompatibility complex
miR	microRNA
MRI	Magnetic Resonance Imaging
NF1	Neurofibromin 1
NFκB	Nuclear factor kappa-light-chain-enhancer of activated B cells
NGS	Next-generation-sequencing
NL	Neoantigen load
NRAS	Neuroblastoma RAS viral oncogene homolog
OS	Overall Survival
PD1	Programmed cell death protein 1
PDL1	Programmed death-ligand 1
PEAs	Proximity extension assays
PFS	Progression Free Survival
PI3K	Phosphoinositol-3-kinase
PIP2	Phosphatidylinositol (4,5)-bisphosphate
PIP3	Phosphatidylinositol (3,4,5)-trisphosphate
PET	Positron Emission Tomography
PTEN	Phosphatase and tensin homolog deleted on chromosome 10
RECIST	Response Evaluation Criteria in Solid Tumours
RFS	Shorter relapse-free survival
RNA-seq	Fast RNA sequencing
STAT3	Signal transducer and activation of transcription-3
TA	Texture analysis
TERC	Telomerase RNA component
TERT	Telomerase reverse transcriptase
TGF-β	Transforming Growth Factor-β
TILs	Tumor-infiltrating lymphocytes
TMB	Tumor mutational burden
VEGF	Vascular endothelial growth factor