Table 1.
CTCs involvement in melanoma clinical trials.
| ID Number | Status | Study Type | Outcome Measure |
|---|---|---|---|
| NCT01528774 | Completed | Observational | CTCs isolation and DNA mutation analysis |
| NCT01573494 | Completed | Interventional | CTCs isolation and evaluation in metastatic melanoma patients, before and after treatment. Contribution of CTCs in patient’s survival. |
| NCT01558349 | Completed | Observational | Comparing the EPISPOT and CellSearch Techniques for CTCs isolation. |
| NCT01776905 | Recruiting | Observational | Evaluation of photoacoustic flow cytometry (PAFC)-based prototype for CTCs isolation. |
| NCT03797053 | Unknown | Observational | Evaluation of CTCs as predictive biomarkers in treatment response |
| NCT01565837 | Unknown | Interventional | Evaluation of CTCs as predictive biomarkers in treatment response |
| NCT02862743 | Active, not recruiting | Interventional | Molecular characterization of advanced melanoma |
| NCT00338377 | Recruiting | Interventional | CTCs analysis and patient’s survival evaluation |
| NCT02071940 | Unknown | Interventional | CTCs analysis and evaluation of response to treatment |
| NCT03007823 | Completed | Interventional | CTCs analysis and patient’s survival evaluation |
| NCT01878396 | Unknown | Observational | Evaluation of CTCs as predictive biomarkers in treatment response |
CTCs: circulating tumor cells; photoacoustic flow cytometry (PAFC).