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. 2021 Apr 7;9(4):398. doi: 10.3390/biomedicines9040398

Figure 4.

Figure 4

Phosphoramidon reduces ER stress and the NLRP3 inflammasome in HK-2 cells. (A) Western blot analysis of ER stress-related protein expression in HK-2 cells. Cells were pretreated with phosphoramidon for 6 h and then treated with 150 nM thapsigargin for 18 h. (B) Western blot analysis of NLRP3 inflammasome-related protein expression in HK-2 cells. Cells were incubated for 24 h with phosphoramidon and 1 µg/mL LPS and then treated with 2 mM ATP for 2 h.