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. 2021 Apr 8;22(8):3852. doi: 10.3390/ijms22083852

Figure 1.

Figure 1

Besides miR-124, human PH-Fibs exhibit significantly decreased levels of let-7i, miR-224 and miR-210, which can be increased by HDACi. qRT-PCR analysis of mature miR-124, let-7i, miR-224, miR-210 and miR-155 levels in human CO- (n = 4) and PH-Fibs (n = 4) (A,C) or in human PH-Fibs treated with DMSO (control) or HDACi (SAHA and apicidin) for 48 h (B,D). Data are presented as mean ± S.E.M, * p < 0.05, ** p < 0.01 PH-Fibs vs. CO-Fibs or PH-Fibs treated with HDACi vs. DMSO.