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Analyses of signaling molecules in Schwann cells treated with dabrafenib. Primary rat Schwann cells were treated with either DMSO (0.1%), dabrafenib (10 µM), or dibutyryl cAMP (500 µM) for 0.5 or 24 h, and the total lysates were subject to Western blot analyses. Band intensities for phosphorylated proteins were quantified using ImageJ and normalized to total protein. Fold changes are indicated at the top of each lane.
