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. 2021 Apr 8;22(8):3861. doi: 10.3390/ijms22083861

Figure 3.

Figure 3

Inhibitory effects of PA on the expression levels of proteins related to melanogenesis in α-MSH-stimulated B16F10 cells. Cells were exposed to 100 nM α-MSH in the presence of PA at the indicated concentrations or 50 µg/mL arbutin. The expression levels of MITF, tyrosinase, TRP-1, and TRP-2 were measured using Western blot analysis and quantified using Image J. Values are expressed as means ± SDs of triplicate experiments (n = 3). Note: ## p < 0.01 compared to the untreated control group; * p < 0.05 and ** p < 0.01 compared to the α-MSH group.