Table 6.

Hub genes (target genes of lncRNAs) and associated lncRNAs in the same module.

mRNA	Module	Function of mRNA	Associated lncRNAs
MED24	Molecular function	Interact with RNA polymerase II to promote formation of transcriptional pre-initiation complex to induce gene expression [17]	MSTRG.2158.2 MSTRG.34993.2 MSTRG.16183.1 MSTRG.17517.2
ANO6	Molecular function	Essential component for calcium-dependent exposure of phosphatidylserine on cell surface, essential for triggering clotting system and deposition in bone mineralization [18]	MSTRG.31383.3 MSTRG.9728.2 MSTRG.33542.1 MSTRG.25050.1 MSTRG.40598.2 MSTRG.18175.1 MSTRG.42141.2 MSTRG.860.1 MSTRG.24048.3 MSTRG.13083.1
ZC4H2	Molecular function	ZC4H2 may improve channel activity and turnover of plasma membrane and is identified as potential candidate for X-linked mental retardation [19]	MSTRG.33542.1 MSTRG.40598.2 MSTRG.11929.4 MSTRG.3259.4
TBPL1	Cellular component	TBPL1 may play an important role in transcription by RNA polymerase II as a component of the transcription factor complex [20]	None
MOGS	Biological process	MOGS may cleave distal alpha-1,2-linked glucose residue from Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor [21]	MSTRG.3283.1
ACADSB	Biological process	Catalyze dehydrogenation of short branched chain acyl-CoA derivatives in metabolism of fatty acids [22,23]	MSTRG.6256.1 MSTRG.22802.1 MSTRG.11451.1 MSTRG.24004.1 MSTRG.26481.9 MSTRG.32831.1 MSTRG.29185.1 MSTRG.3444.1
DNAJC25	Biological process	DNAJC25 may play an important role in cell protection, protein folding, refolding, aggregation and degradation, and protein translocation [24]	MSTRG.3827.1 MSTRG.8329.3 MSTRG.20562.1