Table 1.
Patient # | Age/Sex | CVC | BA | PTN | MV | ID | Surgery | UD | HD (Days) | DTCD | Yeast Species (Isolate #) | AFT * | Outcome |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P94 | 70/F | Yes | Yes | Yes | Yes | No | Brain surgery | Hematological malignancy | 56 | 51 | C. glabrata (#94) | Fluconazole→Caspofungin | Died |
P98 | 40/M | Yes | Yes | Yes | Yes | No | No | None | 83 | 2 7 | C. albicans (#98) | Fluconazole | Died |
P110 | 28/F | Yes | Yes | Yes | Yes | No | No | None | 45 | 6 | C. albicans (#110) | Fluconazole→Caspofungin | Died |
C. albicans (#111) | |||||||||||||
P112 | 68/F | Yes | Yes | Yes | Yes | No | No | None | 6 | 31 | R. mucilaginosa (#112) | CVC removal + Fluconazole | Survived |
P121 | 69/F | Yes | Yes | Yes | Yes | No | No | Endocervical cancer, diabetes | 22 | 4 | C. glabrata (#121) | Fluconazole→Caspofungin | Died |
C. glabrata (#122) | |||||||||||||
P123 | 27/M | Yes | Yes | Yes | No | No | No | None | 17 | 5 | C. albicans (#123) | Fluconazole→Caspofungin | Died |
P124 | 75/M | Yes | Yes | Yes | Yes | No | No | Ovarian cancer | 7 | 1 | C. albicans (#124) | Fluconazole→Caspofungin | Died |
* The loading doses for fluconazole and caspofungin, 800 and 70 mg/day, were de-escalated to 400 and 50 mg/day, respectively. The data on the duration of antifungal treatment were not available. CVC, central venous catheter; BA, broad-spectrum antibiotics; PTN, parenteral nutrition; MV, mechanical ventilation; ID, immunosuppressive drug; HD, hospitalization duration; UD, underlying diseases; DTCD, days to candidemia diagnosis; AFT, antifungal treatment.