Table 3.
Proton assignments, 1H-NMR chemical shifts, and integrations of the βCDNS, 2-amino-4-(4-chlorophenyl)-thiazole (AT) and AT loaded in βCDNS (βCDNS–AT) signals.
| Proton | δβCDNS (ppm) | δβCDNS–AT (ppm) | |Δδ|(ppm) | βCDNS Integration ( ∫) | βCDNS–AT Integration ( ∫) |
| H1 | 4.827 | 4.832 | 0.005 | 7.00 | 7.00 |
| H2 | 3.301 | - | - | 6.98 | - |
| H3 | 3.655 | 3.664 | 0.009 | 6.98 | 7.01 |
| H4 | 3.361 | 3.367 | 0.006 | 7.15 | 7.09 |
| H5 | 3.562 | 3.568 | 0.006 | 7.04 | 7.04 |
| H6 | 3.624 | 3.629 | 0.005 | 13.84 | 13.86 |
| OH2 | 5.713 | 5.717 | 0.004 | 6.68 | 6.70 |
| OH3 | 5.665 | 5.669 | 0.004 | 6.57 | 6.53 |
| OH6 | 4.437 | 4.440 | 0.003 | 6.43 | 6.53 |
| Proton | δAT (ppm) | δβCDNS–AT (ppm) | |Δδ| (ppm) | AT Integration ( ∫) | βCDNS–AT Integration ( ∫) |
| He | 7.061 | 7.061 | 0.000 | 0.99 | 8.49 |
| NH2 b | 7.079 | 7.073 | 0.006 | 2.00 | 16.10 |
| Hb’/f’ | 7.408 | 7.407 | 0.001 | 1.95 | 16.09 |
| Hc’/e’ | 7.803 | 7.801 | 0.002 | 2.00 | 16.52 |