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. 2021 Jan 19;28(5):985–997. doi: 10.1093/jamia/ocaa301

Table 2.

Study results stratified by outcomea

Author, Year b Study Design (Oxford Levels of Evidence) Sample Size (n) Population Intervention (4Ts) Outcomes
Burnout c Satisfaction d Stress e
Agha, 201014 NR (IV) 9 Specialistsf,g,h Technology ↓*
Amis, 201817 Pre-post survey (IV) 13 First year residents Time, Transitions ↑*
Babbott, 201320 Prospective (IV) 422 IM and FM physicians Technology NS NS ↑+
Baccei, 202021 Pre-post survey (IV) 6 Radiologists Time, Teamwork, Transitions - ↑* -
Beam, 201722 Pre-post survey (IV) 158 Physicians Technology NS
Chapman, 201727 Cross-sectional (IV) 886 PC physicians Teamwork, Transitions ↑*
Contratto, 201529 Pre-post survey (IV) 9 PC physicians Time, Teamwork, Transitions ↓*
Contratto, 201728 Quasi-experimental mixed methods (IV) 7 IM physicians Time, Teamwork, Transitions ↓*
Danila, 201830 Pre-post survey (IV) 6 Specialistsg, h Teamwork, Transitions NS
Dunn, 200732 Prospective study (IV) 22–32 Physicians Time, Teamwork, Transitions ↓++ NS
Ehrlich, 201635 Pre-post survey (IV) 25 Ophthalmologists Time NS
Gidwani, 201739 RCT (IB) 4 Physicians Time, Teamwork, Transitions ↑+++
Goyal, 201841 Prospective cohort (IIB) 7 IM physicians (including residents) Time, Teamwork, Transitions, Technology ↑+++
Heaton, 201643 Systematic review (IIA) NA NA Time, Teamwork ↑*
Heyworth, 201244 Pre-post survey (IV) 163 PC and specialty Technology ↑+
Hung, 201845 l Pre-post survey (IV) 680 Physicians Teamwork, Transitions ↑+++ ↑+ ↑+++
Imdieke, 201746 Quasi-experimental pre-post intervention study (IV) 2 IM physicians Time, Teamwork, Transitions ↑+++
Joseph, 201749 Pre-post survey (IV) NR Providers Time, Transitions Technology ↑*
Keefer, 201851 Pre-post survey (IV) NR Physicians Time, Teamwork, Transitions - - ↓*
Koshy, 201053 Static-group comparison study (IV) 5 Urologists, residents Teamwork, Transitions ↑+++
Lapointe, 201856 Pre-post survey (IV) 25 IM residents Time, Transitions, Technology ↑* ↓*
Lee, 201857 Pre-post survey (IV) 15 Neuroradiologists and fellows Transitions ↑+++ ↓+++
Linzer, 201559 Cluster RCT (IIB) 135 FM and IM physicians Teamwork, Transitions ↓+ NS NS
Linzer, 201758 Cluster RCT (IIB) 165 FM and IM physicians Teamwork, Transitions ↑+++ ↓+++
Mazur, 201962 Prospective cohort (IIB) 38 IM, FM, and specialisti, j, k residents and fellows Time, Transitions, Technology - NS -
McCormick, 201863 Pre-post survey (IV) 6 Urologists Time, Teamwork, Transitions ↑+
Mehta, 201864 Pre-post survey (IV) NR Hospitalists Time, Teamwork, Transitions, Technology - ↑* -
Menachemi, 200965 Cross-sectional (IV) 4,203 PC physicians and clinical specialists Technology ↑++
Michelotti, 201366 Pre-post survey (IV) 59 Faculty ophthalmologists Technology - ↓+++ -
Milenkiewicz, 201767 Pre-post survey (IV) NR Physicians Time, Technology ↑*
Mishra, 201870 Crossover prospective cohort study (IIB) 18 PC providers Time, Teamwork, Transitions - ↑*
Payne, 201875 RCT (IIB) 31 IM residents and attending hospitalists Technology - NS
Pierce, 201776 Pre-post survey (IV) 55 Physicians and advanced practice clinicians Teamwork, Transitions ↓*
Pozdnyakova, 201877 Prospective, pre-post-pilot study (IV) 6 General IM faculty Teamwork, Transitions, Technology NS
Shaw, 201783 Pre-post survey (IV) NR Medical doctors Teamwork, Transitions NS
Willard-Grace, 201792 Cross-sectional (IV) 236 Clinicians Time, Teamwork, Transitions ↓++
Wylie, 201493 Cross-sectional (IV) 2365 PC providers Technology ↓+

Note: The arrows indicate the directionality of the intervention on the effect of burnout, satisfaction, and stress. Improvements are denoted by green color where the associations of the intervention on burnout or proxy measures were statistically significant (see below). Red color indicates the intervention did not improve the burnout or proxy measure (interpreted by a nonsignificant result or P values were not provided) or resulted in detractions whereby the outcome measure worsened with the intervention. White content with dashes indicates no data was reported. Levels of evidence: IB, Individual randomized controlled trial (RCT) (with narrow confidence interval); IIA, Systematic review with homogeneity; IIB, Individual cohort study (including low RCT; eg, < 80% follow-up); IV, Case-series, poor-quality cohort, case-control studies, and systematic review with heterogeneity.

a

Table adapted from DeChant et al (2019).10

b

DeChant et al. (2019) was not included in this table as the relevant interventions are already included in the table under the original author names.10

c

Burnout includes overall burnout, emotional exhaustion, depersonalization, personal accomplishment, and cynicism.

d

Satisfaction includes outcomes reported as satisfaction, professional fulfillment, well-being, and joy of practice.

e

Stress includes outcomes reported as stress, psychological strain, and job distress.

f

Pulmonology, grheumatology, hendocrinology, ipediatrics, jsurgery, or kother specialists.

l

Hung et al. describe findings of increased engagement, teamwork, and stress suggesting that their work redesign improved physician experiences, but not sufficiently to overcome workflow challenges linked to stress and burnout.

Symbols: + = P < .05; ++ = P < .01; +++ = P < .001; NS = Not significant; * = No P value reported. FM = Family medicine; IM = Internal medicine; NA = Not applicable; NR = Not reported; NS = Not significant; PC = Primary care.