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. Author manuscript; available in PMC: 2021 Apr 24.
Published in final edited form as: Eur J Nucl Med Mol Imaging. 2019 Aug 10;46(12):2545–2557. doi: 10.1007/s00259-019-04434-0

Fig. 4.

Fig. 4

a and e SPECT/CT imaging 177Lu-L1 and 177Lu-L14 (37 MBq) in PSMA(+) PC3 PIP and PSMA(−) PC3 flu tumor bearing mouse during 2–192 h (n = 2). b Representative IHC staining of PSMA expression. c γ-H2A.X staining to demonstrate DNA damage (scale bar: 50 μm, 20X). d H&E staining of whole tumor issue sections within the PSMA(+) PC3 PIP tumor for untreated control and after administration of 177Lu-L1 24 h, 7 and 12 d (left to right) (scale bar:660μm, 2X)