Table 2.
Overall analysis of study population (data are expressed in median, range, and number or percentage; PFS, progression-free survival; OS, overall survival).
| Variables | N | Median PFS | Median OS | P value |
|---|---|---|---|---|
| Overall | 20 | 16 months (7.2–20.6 months) | 38 months (32–44 months) | |
| Anatomic site | ||||
| Oral cavity | 12 (60%) | 34.5 months | ||
| Hypopharynx | 6 (30%) | 38 months | ||
| Oropharynx | 2 (10%) | 35 months | ||
|
| ||||
| Overall response rate after induction | 75% | P < 0.001 | ||
| Complete response | 2 (10%) | |||
| Partial response | 13 (65%) | |||
| Stable disease | 2 (10%) | |||
| Progressive disease | 3 (15%) | |||
|
| ||||
| Overall response rate after CRT | 65% | P − 0.192 | ||
| Complete response | 6 (30%) | Not reached | Not reached | |
| Partial response | 7 (35%) | 17.6 months | 34.5 months | |
| Stable disease | 2 (10%) | 8.1 months | 31 months | |
| Progressive disease | 5 (25%) | 6.7 months | 17 months | |