Table 5.
Multiple linear regression models regressing inflammatory biomarkers on life course SES trajectories and daily discrimination
| Variable | CRP (ln) | IL-6 (ln) | Fibrinogen | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Model 1 | Model 2 | Model 3 | Model 1 | Model 2 | Model 3 | |
| Black adults (n = 215) | |||||||||
| SES Trajectories | |||||||||
| Objectively Stable low | 0.38 (0.13) |
0.37 (0.20) |
0.27 (0.18) |
0.35 (0.11)** |
0.30 (0.12)* |
0.24 (0.12)* |
12.96 (14.86) |
9.19 (16.19) |
2.54 (15.25) |
| Downwardly Mobile | 0.13 (0.23) |
0.23 (0.23) |
0.17 (0.21) |
0.29 (0.14)* |
0.30 (0.14)* |
0.24 (0.13) |
14.71 (18.30) |
17.33 (19.01) |
12.43 (17.90) |
| Upwardly Mobile | — | — | — | — | — | — | — | — | — |
| Daily | 0.04 | 0.04 | 0.02 | 0.00 | 0.00 | −0.01 | 2.81 | 2.85 | 1.54 |
| Discrimination | (0.01)** | (0.01)** | (0.01) | (0.01) | (0.01) | (0.01) | (1.03)** | (1.06)** | (1.02) |
| Intercept | 0.47 | 1.02 | −0.50 | 0.56 | 0.52 | −0.39 | 295.2*** | 291.1*** | 181.3** |
| Model FR2(%) | 3.54** 8.1 |
2.58** 11.9 |
6.30*** 32.1 |
3.58** 8.0 |
3.16** 14.0 |
4.51*** 24.9 |
4.68*** 10.4 |
2.52** 11.6 |
4.28*** 24.2 |
| White adults (n = 985) | |||||||||
| SES Trajectories | |||||||||
| Objectively Stable low |
0.39 (0.15)* |
0.30 (0.15) |
0.11(0.14) |
0.27 (0.10)** |
0.19 (0.10) |
0.09 (0.09) |
25.80 (10.89)* |
19.50 (11.19) |
12.13 (10.93) |
| Subjectively downward |
0.37 (0.12)** |
0.33 (0.12)* |
0.17 (0.11) |
0.13 (0.07) |
0.10 (0.07) |
0.03 (0.07) |
17.90 (8.33)* |
14.67 (8.45) |
6.84 (8.23) |
| Upwardly mobile |
0.23 (0.09)** |
0.22 (0.08)* |
0.11 (0.08) |
0.06 (0.05) |
0.05 (0.05) |
0.00 (0.05) |
13.89 (6.09)* |
13.23 (6.10)* |
8.87 (5.92) |
| Stable high | — | — | — | — | — | — | — | — | — |
| Daily Discrimination | 0.01 (0.01) |
0.01 (0.01) |
−0.00 (0.01) |
0.01 (0.01) |
0.01 (0.01) |
0.00 (0.01) |
0.14 (0.65) |
−0.07 (0.68) |
−0.54 (0.67) |
| Intercept | −0.13 (0.23) |
0.57 (0.29) |
−1.73*** | −0.34* | 0.05 | −0.89 (0.19)*** |
275.76*** | 306.5 (21.16) |
207.1*** |
| Model F | 7.15*** | 7.06*** | 19.53*** | 13.33*** | 9.89*** | 16.34*** | 9.76*** | 6.17*** | 9.23*** |
| R2 (%) | 4.3 | 7.6 | 23.7 | 7.7 | 10.2 | 20.6 | 5.8 | 6.7 | 12.8 |
Note: Model 1 = adjusted for age and sex; Model 2 = adjusted for age, sex, depressive symptomology, perceived stress, smoking status, physical activity; Model 3 = adjusted for age, sex, depressive symptomology, perceived stress, smoking status, physical activity, BMI, total : HDL cholesterol ratio, elevated BP status, and insulin resistance status; Upwardly Mobile was a reference group for Black group and Stable High was a reference group for white group.
*
= p < .05
**
= p < .01
***
= p < .001.