Table 2.

Significance of sex differences in naïve and corrected linear regression models for ACE-R total and sub-domain scores

ACE-R variable	Total mean (n = 392)a	Male mean (n = 253)a	Female mean (n = 139)a	Naïve (p value)b	Covariate corrected (p value)
Total ACE-R	88.89 (10.83)	88.24 (10.53)	90.07 (11.29)	0.098	0.044c
Attention and orientation	17.37 (1.59)	17.28 (1.61)	17.53 (1.54)	0.143	0.289d
Memory	22.26 (3.77)	21.93 (3.96)	22.85 (3.33)	0.017	0.030e
Fluency	9.98 (3.33)	9.60 (3.55)	10.66 (2.77)	0.002	0.006f
Language	24.82 (1.94)	24.65 (2.11)	25.12 (1.56)	0.018	0.067g
Visuospatial-perceptual	14.66 (2.49)	14.55 (2.72)	14.85 (1.98)	0.253	0.685h

^aData are presented as mean raw scores (SD)

^bp value taken from GLM without correction for covariates

^cCorrected for age at assessment, age at onset, disease duration and LEDD, identified in Supplementary Table 1

^dCorrected for age at assessment, disease duration, LEDD and DBS status, identified in Supplementary Table 1

^eCorrected for age at assessment, age at onset, disease duration and DBS status, identified in Supplementary Table 1

^fCorrected for age at assessment, disease duration and DBS status, identified in Supplementary Table 1

^gCorrected for age at assessment, age at onset, disease duration and LEDD, identified in Supplementary Table 1

^hCorrected for age at assessment, disease duration and DBS status, identified in Supplementary Table 1

ACE-R, Addenbrooke’s Cognitive Examination—Revised; SD, standard deviation