. 2021 Jan 5;268(5):1903–1912. doi: 10.1007/s00415-020-10367-8

Table 4.

Significance of sex differences in naïve and corrected generalised linear mixed models for total ACE-R total and sub-domain scores over time

ACE-R	Males at baseline (n = 80)^a	Females at baseline (n = 47)^a	Males at follow-up (n = 80)^a	Females at follow-up (n = 47)^a	Naïve (p value)^b	Corrected (p value)
Total ACE-R	89.00 (8.56)	91.85 (6.99)	85.98 (12.53)	90.48 (6.99)	0.005	0.001^c
Attention and orientation	17.26 (1.28)	17.64 (1.44)	17.04 (1.89)	17.34 (1.03)	0.069	0.049^d
Memory	21.49 (3.77)	23.00 (3.51)	20.59 (4.85)	21.91 (3.73)	0.006	0.002^e
Fluency	10.06 (3.44)	10.77 (2.53)	10.49 (2.99)	11.70 (2.44)	0.011	0.004^f
Language	25.05 (1.31)	25.32 (1.14)	23.72 (3.23)	24.49 (1.71)	0.064	0.040^g
Visuospatial-perceptual	14.71 (2.31)	15.40 (1.12)	14.21 (2.75)	14.72 (1.79)	0.028	0.011^h

^aData are presented as mean raw scores (SD)

^bp value taken from GLMM without correction for covariates

^cCorrected for age at assessment and age at onset, as identified in Supplementary Table 3

^dCorrected for age at assessment and age at onset, as identified in Supplementary Table 3

^eCorrected for age at assessment and age at onset, as identified in Supplementary Table 3

^fCorrected for age at assessment and age at onset, as identified in Supplementary Table 3

^gCorrected for years between assessments, age at assessment and age at onset, as identified in Supplementary Table 3

^hCorrected for years between assessments, age at assessment and age at onset, as identified in Supplementary Table 3

ACE-R Addenbrooke’s cognitive examination—revised, SD standard deviation