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. 2021 Jan 9;268(5):1962–1971. doi: 10.1007/s00415-020-10383-8

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Voxel-based morphometry results of cross-sectional grey matter (GM) comparison between subjects with Cardiovascular Risk Factors, Aging, and Dementia risk (CAIDE) score > 6 (n = 68) and subjects with CAIDE score ≤ 6 (n = 92) at baseline. Areas in red-yellow represent areas, where the GM volume was lower in subjects with CAIDE score > 6 than subjects with CAIDE score ≤ 6 (family-wise error corrected P < 0.05), adjusting for age, gender, education years and total intracranial volume