Table 3.
VBM results of GM volume comparison between subjects with CAIDE score > 6 and subjects with CAIDE score ≤ 6
| Anatomical region | Cluster size (voxels) | Coordinates (MNI) | FWE-corrected P value | ||
|---|---|---|---|---|---|
| x | y | z | |||
| Cross-sectional | |||||
| Temporal, occipital and fusiform cortex; Lingual gyrus | 39 | − 24 | − 54 | − 10.5 | 0.047 |
| Longitudinal | |||||
| Supramarginal gyrus; Angular gyrus | 4109 | 51 | − 42 | 34.5 | 0.020 |
| Precuneus | 2270 | 15 | − 57 | 25.5 | 0.031 |
| Lateral occipital cortex | 342 | 43.5 | − 79.5 | − 1.5 | 0.038 |
| Superior parietal lobule | 92 | − 25.5 | − 54 | 49.5 | 0.039 |
| Cingulate gyrus | 46 | 3 | − 37.5 | 33 | 0.049 |
CAIDE Cardiovascular Risk Factors, Aging, and Dementia risk, FWE family-wise error, GM grey matter, MNI Montreal Neurological Institute, VBM voxel-based morphometry