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. 2020 Dec 22;268(5):1728–1737. doi: 10.1007/s00415-020-10356-x

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Dopaminergic medications, quality of life, and time in “on” in LE-PD and Control-PD. Total and Dopamine-agonists (D-Ag) Levodopa Equivalent Daily Dose (LEDD) (a, b), PDQ-8 summary index (SI) and time spent in ON (c, d) before and after Levodopa–Carbidopa Intrajejunal Gel Infusion (LCIG) in “Late elderly” Parkinson’s disease (LE-PD) and Control-PD. After LCIG, a significant decrease of D-Ag LEDD and PDQ-8 and a significant increase of time spent in ON were achieved, without differences between LE-PD and Control-PD