Table 3.
Adverse Reactions (ADR) in Late Elderly (LE) and Control Parkinson’s Disease subjects treated with Levodopa–Carbidopa Intrajejunal gel infusion
| LE-PD (Y/N) | Control-PD (Y/N) | p value | |
|---|---|---|---|
| ADR (> 5 events per patient) | 5/20 | 8/17 | 0.5 |
| Stoma infection | 3/22 | 7/18 | 0.289 |
| Abdominal pain | 0/25 | 0/25 | > 0.9999 |
| Incision site erythema or granulomatosis | 10/15 | 12/13 | 0.7761 |
| Complications of device insertion | 1/24 | 2/23 | > 0.9999 |
| Peritonitis | 0/25 | 0/25 | > 0.9999 |
| Duodenal ulcer | 0/25 | 1/24 | > 0.9999 |
| Failure of the infusion system | 2/23 | 5/20 | 0.4174 |
| Tube dislocation | 10/15 | 6/19 | 0.3635 |
| Tube coiling, kinking and occlusion | 9/16 | 10/15 | > 0.9999 |
| Unintentional removal of tube by the patient | 1/24 | 6/19 | 0.0983 |
| Hallucinations | 7/18 | 6/19 | > 0.9999 |
| Delusions | 3/22 | 3/22 | > 0.9999 |
| Polyneuropathy | 8/17 | 7/18 | > 0.9999 |
| Delirium | 3/22 | 3/22 | > 0.9999 |
| Weight loss | 12/13 | 12/13 | > 0.9999 |
| Taste impairment | 0/25 | 2/23 | 0.4898 |
| Moderate/severe dyskinesia | 9/16 | 11/14 | 0.7733 |