Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 17;5(4):nzab025. doi: 10.1093/cdn/nzab025

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021. Published by Oxford University Press on behalf of the American Society for Nutrition.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Cellular localization of Tfrc and Fpn1 in the mouse placenta. IHC staining showing Tfrc expression in SCTB I (A) and Fpn1 expression in SCTB II (B) of E15.5 mouse placenta. Scale bar, 10 μm. High magnification immunogold EM images showing Tfrc on membranes of intracellular vesicles in SCTB and to a lesser extent on fetal endothelium (arrows) (C) and Fpn1 along the basal membrane of SCTB II (arrows) (D). Scale bar, 0.5 μm. (E) Updated mechanism of placental iron transport in the mouse placenta. DMT1, divalent metal transporter 1; E, embryonic day; EM, electron microscopy; fc, fetal capillary; fE, fetal endothelium; Fpn1, ferroportin 1; IHC, immunohistochemistry; mbs, maternal blood space; SCTB, syncytiotrophoblast; Tfrc, transferrin receptor.