Table 1.

Baseline characteristics of cohort presented as overall and by the occurrence of the primary outcome.

	Overall n=708	Any adverse event n=186	No adverse event n=522	Difference (95% CI)
Age (Mean (SD))	62.2 (18.1)	67.1 (16.8)	60.4 (18.3)	6.7 (3.8,9.6)
Male gender (n [%])	408 [57.6]	116 [62.4]	292 [55.9]	6.4 (-2.1, 14.9)
Ethnicity (n [%])
White	288[40.7]	86 [46.2]	202 [38.7]	7.5 (-1.1, 16.2)
Black	196[27.7]	46 [24.7]	150 [28.7]	-4.0 (-11.7, 3.7)
Asian	55 [7.8]	19 [10.2]	36 [6.9]	3.3 (-1.9, 8.5)
Mixed/Other	51[7.2]	16 [8.6]	35 [6.7]	1.9 (-3.0, 6.8)
Not specified	118 [16.7]	19 [10.2]	99 [19.0]	-8.8 (-14.6, -2.9)
Body Mass Index (Mean (SD))	27.4 (6.8)	27.5 (6.7)	27.3 (6.9)	0.2 (-0.9, 1.3)
Elixhauser Comorbidity (n [%])
Total condition count of 10+	53 [7.5]	20 [10.8]	33 [6.3]	4.4 (-0.8, 9.7)
Total condition count of 7-9	82 [11.6]	20 [10.8]	62 [11.9]	-1.1 (-6.7, 4.5)
Total condition count of 4-6	158 [22.3]	46 [24.7]	112 [21.5]	3.3 (-4.2, 10.8)
Total condition count of 1-3	310 [43.8]	64 [34.4]	246 [47.1]	-12.7 (-21.1, -4.3)
Missing	105 [14.8]	36 [19.4]	69 [13.2]	6.1 (-0.6, 12.9)
Diabetes (n [%])	272 [38.4]	72 [38.7]	200 [38.3]	0.4 (-8.1, 8.9)
Global Frailty Score (Mean (SD))	3.5 (2.2)	3.7 (2.1)	3.5 (2.3)	0.2 (-0.2,0.6)