Figure 9.

Supervised multivariate analysis indicating a clear inter-class discrimination. The score plot from Orthogonal partial least squares discriminant analysis (OPLS-DA) are represented by individual comparison. The data from three biological repeats were analyzed. (A) OPLS-DA score plot for the basal antimony resistant phenotype changes. (B) OPLS-DA score plot for the resistant strain responding to Sb^III. (C) OPLS-DA score plot for the sensitive strain responding to Sb^III. All models were successfully validated by one thousand permutations getting optimal Q2 and R2Y scores without any evidence of overfitting. Each individual marker represents a biological replicate. Total variance explained (TVE) in summarized. The 95% confidence ellipse using Hotelling T-squared is represented.