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(A) Prognostic genomic alterations identified in ATLL. Red stars denote alterations related to prognosis in ATLL. (B) Difference of PD-L1 expression patterns on ATLL prognosis. Left: PD-L1 can be expressed through genomic alterations, including the amplification and 3’UTR disruption of PD-L1 on the surface of ATLL cells. Right: stromal cells in the tumor-microenvironment express PD-L1 and the cases are associated with favorable prognosis.
