Table 3.

Histological changes at specific IRE setting and time course following IRE in normal porcine pancreas [23,24,99].

Time	Electrode Type	Probe No	Inter-Electrode Distance (mm)	Pulse No	Pulse Length (ms)	Voltage (Volts)	Ablation Zone (mm2)	Histology
1 h	Monopolar	2	10	90	90	1900	Not stated	Oedema Necrosis
2 h	Monopolar	2	10	90	100	1500	240	Necrosis
24 h	Monopolar	2	10	70	70	2000	134	Necrosis
24 h	Bipolar	1	7	90	70	2100	271	Necrosis
48 h	Monopolar	2	9	90	100	1500	252	Necrosis
72 h	Monopolar	2	20	90	100	3000	Not stated	Necrosis
7 days	Monopolar	2	10	90	90	1900	Not stated	Apoptosis Necrosis
7 days	Monopolar	2	15	90	70	2700	Not stated	Necrosis
14 days	Monopolar	2	10	90	100	1500	<100	Fibrosis
14 days	Monopolar	2	15	90	100	1500	Not seen	No changes
14 days	Monopolar	2	15	70	100	2250	Not seen	No changes
14 days	Monopolar	2	10	70	70	2000	Not seen	No changes
14 days	Not specified	-	Not specified	100	100	2500	Not stated	Necrosis
14 days	Monopolar	2	15	90	100	2300	Not stated	Necrosis Apoptosis
28 days	Monopolar	2	15	90	100	2500	21	Atrophy Fibrosis
28 days	Bipolar	1	7	90	70	2400	207	Atrophy Fibrosis