Table 4.
Histological changes at specific IRE settings and time course following IRE to murine pancreatic cancer models [100,101,102].
| Time | Electrode Type | Probe No | Inter-Electrode Distance (mm) | Pulse No |
Pulse Length (ms) |
Voltage (Volts/cm) | Ablation Zone (mm2) | Histology |
|---|---|---|---|---|---|---|---|---|
| 0.5 h | Not specified | - | Not specified | 64 | 100 | 1250 | Not stated |
Necrosis Apoptosis |
| 24 h | Not specified | - | Not specified | 100 | 100 | 2500 | Not stated | Necrosis No evidence of apoptosis |
| 24 h | Not specified | - | 5 | 90 | 100 | 800 | Not stated | Necrosis Apoptosis |
| 72 h | Not specified | - | 5 | 90 | 100 | 800 | Not stated | Necrosis Apoptosis |
| 7 days | Not specified | - | Not specified | 100 | 100 | 2500 | Not stated | Necrosis No evidence of apoptosis |
| 7 days | Not specified | - | 5 | 90 | 100 | 800 | Not stated | Necrosis Apoptosis |
| 14 days | Not specified | - | Not specified | 100 | 100 | 2500 | Not stated | Necrosis No evidence of apoptosis |