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Colony formation capacity of breast cancer cells after hTERT downregulation in a long-term study. The clonogenic potential of MCF7 (A) and MDA-MB-231 (B) after treatment with doxorubicin was determined. Cells were subjected to experiment on 21st-day post-transduction. The representative images of single-cell clone proliferation, stained with Giemsa’s solution. Data are presented as the mean ± standard deviation. (*) p < 0.05 relative to shRNA Control.
