Table 3.

DDI prediction for warfarin and naproxen at the level of cytochrome P450 isoforms.

Isoforms of Cytochrome P450	Pa	Pi	ΔP
Interaction CYP2C9	0.382	0.018	0.364
Interaction CYP2C19	0.174	0.346	−0.172
Interaction CYP2C8	0.017	0.313	−0.296
Interaction CYP2D6	0.057	0.406	−0.349
Interaction CYP2B6	0.04	0.553	−0.513
Interaction CYP1A2	0.011	0.617	−0.606
Interaction CYP3A4	0.004	0.739	−0.735