Table 2.
Measurements | Supplementation | |
---|---|---|
Iron | Measurement of iron storage status is recommended: -at discharge -during follow-up -at the beginning of complementary feeding |
Iron supplementation should be tailored according to: -birth weight -gestational age -type of feeding -need for catch up growth -iron status |
Zinc | Serial measurements of zinc concentration are not recommended unless evidence of zinc deficiency is detectable | Zinc supplementation through the first year of life may be advisable, particularly in breastfed infants with impaired growth |
Vitamin D | Serial measurements of Vitamin D are not recommended, unless specific risk factors are identified | Vitamin D supplementation is recommended at least up to the first year of life |
LCPUFAs | Serial measurements of LCPUFA, particularly DHA and AA, are not recommended | DHA supplementation may be advisable but there is no sufficient evidence to advise specific timing and doses |
Calcium and Phosphorus | Serial measurements of serum calcium, phosphate, alkaline phosphatase (ALP), parathormone (PTH) and vitamin D are not recommended but may be advisable in VLBW infants in the first weeks after discharge. Assessment of urinary calcium and phosphate to creatinine ratios may be useful. | Calcium 140–160 mg/100 kcal (AAP) 70–140 mg/100 kcal (ESPGHAN) Phosphorus 95–108 mg/100 kcal (AAP) 50–86 mg/100 kcal (ESPGHAN) |
AAP: American Academy of Pediatrics; ESPGHAN: European Society for Pediatric Gastroenterology, Hepatology and Nutrition; VLBW: Very Low Birth Weight.