Figure 3.

(a) In vivo fluorescence imaging of mice after subcutaneous injection of AuNCs with emission at 450 nm, 520 nm, and 705 nm. (b) Time course in vivo fluorescence imaging of human breast cancer bearing mice (MDA-MB-231) after injection of AuNC₇₀₅. The renal clearance of AuNC₇₀₅ (blue circle, bladder) and the long retention time in tumor (white circle) are highlighted. (c) NIR-fluorescence-guided intraoperative surgery after AuNC₇₀₅ injection, showing the tumor that was surgically exposed and sequentially removed until the entire tumor was completely removed. Adapted with permission from [69], published by Springer Nature.