Table 3.
Sperm nuclear alterations observed in case and control groups.
| Sperm Nuclear Alterations |
Case Group | Control Group | p | ||
|---|---|---|---|---|---|
| mean ± s.d | Spz Number |
mean ± s.d | Spz Number |
||
| Cytoplasmic ROS | 24.3 ± 20.7 | 507 ± 151 | 9.4 ± 7.4 | 540 ± 133 | 0.039 |
| (%) | |||||
| Nuclear ROS | 30.3 ± 20.3 | 507 ± 151 | 26.1 ± 13.3 | 540 ± 133 | 0.66 |
| (%) | |||||
|
8-OHdG
positive spz |
3.9 ± 2.8 | 536 ± 46 | 3.0 ± 2.3 | 542 ± 72 | 0.7 |
| (%) | |||||
|
DNA
fragmentation |
9.8 ± 6.4 | 569 ± 151 | 7.1 ± 5.3 | 591 ± 164 | 0.49 |
| (%) | |||||
| Aneuploidy | 0.3 ± 0.2 | 5277 ± 74 | 0.4 ± 0.2 | 5249 ± 142 | 0.28 |
| (%) | |||||
| Diploidy | 0.3 ± 0.2 | 5277 ± 74 | 0.3 ± 0.2 | 5249 ± 142 | 0.99 |
| (%) | |||||
|
Total
Chromosome abnormalities |
0.7 ± 0.3 | 5277 ± 74 | 0.8 ± 0.4 | 5249 ± 142 | 0.7 |
| (%) | |||||
|
Abnormal
chromatin condensation |
15.2 ± 8.2 | 542 ± 110 | 9.3 ± 4.2 | 624 ± 114 | 0.006 |
| (%) | |||||
|
Mean number
of telomeres |
21.7 ± 4.3 | 200 ± 18 | 18.8 ± 3.0 | 214 ± 15 | 0.049 |
| (Fluorescent signals per spz) |
|||||
|
Relative
Telomere length |
59.6 ± 30.7 | 200 ± 18 | 65.8 ± 26.5 | 214 ± 15 | 0.7 |
| (FRU) | |||||
8-OHdG: 8-oxo-deoxyguanosine; FRU: fluorescence relative units; ROS: reactive oxygen species; s.d.: standard deviation; spz: spermatozoa; %: percent.