Figure 7.

(A) MRI and FET-PET images of a patient with melanoma brain metastasis, diagnosed with PsP using immune-related response criteria (irRC) after receiving immune checkpoint inhibitor immunotherapy. The index MRI shows >25% increase in contrast-enhancing lesions located in frontal and occipital regions. Low metabolic tumor activity was observed on FET-PET images. (B) MRI and FET-PET images of a patient with melanoma brain metastasis, who was diagnosed with TP using irRC. The index MRI shows >25% increase in contrast-enhancing lesions located in the body of corpus callosum and occipital regions. A very high metabolic tumor activity was observed on FET-PET images. Reprinted with permission from ref. [109]. Copyright 2016 Oxford University Press.